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Gestational diabetes mellitus, epigenetic age and offspring metabolism.

Catherine KimKylie K HarrallDeborah H GlueckBelinda L NeedhamDana M Dabelea
Published in: Diabetic medicine : a journal of the British Diabetic Association (2022)
In this study, children exposed to GDM experience greater extrinsic EAA, which is associated with lower insulin sensitivity and greater insulin secretion. Further studies are needed to determine the directionality of these associations.
Keyphrases
  • pregnant women
  • dna methylation
  • young adults
  • gene expression
  • high fat diet
  • type diabetes
  • metabolic syndrome
  • adipose tissue
  • insulin resistance
  • skeletal muscle