Association between renal failure and red blood cell alloimmunization among newly transfused patients.

Josine A OudDorothea EversRutger A MiddelburgKaren M K de VooghtDaan van de KerkhofOtto VisserNathalie C V PéquériauxFrancisca HudigJohanna G van der BomJaap Jan Zwaginga

Published in: Transfusion (2020)

These findings are indicative of a weakened humoral response in acute as well as chronic renal failure, which appeared to be most pronounced when treated with RRT. Future research should focus on how renal failure and RRT mechanistically modulate RBC alloimmunization.

Keyphrases

red blood cell
end stage renal disease
newly diagnosed
ejection fraction
immune response
chronic kidney disease
sickle cell disease
liver failure
prognostic factors
drug induced
respiratory failure
patient reported outcomes
extracorporeal membrane oxygenation