Common inherited variants of PDCD1, CD274 and HAVCR2 genes differentially modulate the risk and prognosis of adenocarcinoma and squamous cell carcinoma.

Nafeesa Moksud Marta Wagner Konrad Pawełczyk Irena PorębskaBeata Muszczyńska-BernhardAneta Kowal Andrzej Wiśniewski Monika Kosacka Julia Kończak Paweł KarpińskiDominik FrydrykAnna Andrzejczak Lidia Karabon Piotr Kuśnierczyk Monika Jasek

Published in: Journal of cancer research and clinical oncology (2023)

Our results provided additional evidence that SNPs of genes for PD-1, PD-L1 and TIM-3 differentially modulate the risk and prognosis of LUSC and LUAD.

Keyphrases

squamous cell carcinoma
genome wide
locally advanced
copy number
dna methylation
bioinformatics analysis
radiation therapy