BRCC36 regulates β-catenin ubiquitination to alleviate vascular calcification in chronic kidney disease.

Yalan LiXiaoyue ChenYiqing XiongXueqiang XuCaidie XieMin MinDongmei LiangCheng ChenHuijuan Mao

Published in: Journal of translational medicine (2024)

Our research results emphasize the critical role of the BRCC36-β-catenin axis in VC, suggesting that BRCC36 or β-catenin may be promising therapeutic targets to prevent the progression of VC in CKD patients.

Keyphrases

end stage renal disease
chronic kidney disease
epithelial mesenchymal transition
cell proliferation
ejection fraction
newly diagnosed
peritoneal dialysis