Pharmacokinetics, Bioavailability, and Tissue Distribution of the Kirsten Rat Sarcoma Inhibitor Adagrasib in Rats Using UPLC-MS/MS.
Pan LeiWanying ShenHuijuan TangLi YouGuoyi ChenYijun TangWei Lu
Published in: Drug design, development and therapy (2024)
Adagrasib was slowly absorbed and cleared rapidly, and it was also widely distributed in vivo. This study provides a potential reference for adagrasib in clinical studies.