Effects and Mechanisms of Fisetin Against Ischemia-reperfusion Injuries: A Systematic Review.

Omid-Ali Adeli Saeid Heidari-Soureshjani Sahar Rostamian Zahra Azadegan-Dehkordi Armin Khaghani

Published in: Current pharmaceutical biotechnology (2024)

Fisetin, by antioxidant, anti-inflammatory, mitochondrial protection, promoting autophagy, and anti-apoptotic properties, can reduce cell injury due to myocardial, cerebral renal, and hepatic IRIs without any significant side effects.

Keyphrases

anti inflammatory
oxidative stress
cell death
single cell
subarachnoid hemorrhage
cell therapy
signaling pathway
stem cells
mesenchymal stem cells
brain injury
cerebral ischemia
cerebral blood flow