Characterization of the interaction between platelet factor 4 and homogeneous synthetic low molecular weight heparins.
Thi-Huong NguyenYongmei XuSven BrandtMartin MandelkowRicarda RaschkeUlrike StrobelMihaela DelceaWen ZhouJian LiuAndreas GreinacherPublished in: Journal of thrombosis and haemostasis : JTH (2019)
We provide a template for characterizing interactions of newly developed heparin-based anticoagulant drugs with proteins, especially PF4 and the resulting potential antigenicity.