The viral capsid as novel nanomaterials for drug delivery.
Alaa A A AljabaliSk Sarif HassanRitesh M PabariSeyed H ShahcheraghiVijay MishraNitin B CharbeDinesh K ChellappanHarish DurejaDinesh Kumar ChellappanAbdulmajeed G AlmutaryAbdullah M AlnuqaydanSuresh K VermaPritam K PandaYogendra Kumar MishraÁngel Serrano-ArocaKamal DuaVladimir N UverskyElrashdy M RedwanBojlul BaharAmit BhatiaPoonam NegiRohit GoyalPaul McCarronHamid A BakshiMurtaza M TambuwalaPublished in: Future science OA (2021)
The purpose of this review is to highlight recent scientific developments and provide an overview of virus self-assembly and viral particle dynamics. Viruses are organized supramolecular structures with distinct yet related features and functions. Plant viruses are extensively used in biotechnology, and virus-like particulate matter is generated by genetic modification. Both provide a material-based means for selective distribution and delivery of drug molecules. Through surface engineering of their capsids, virus-derived nanomaterials facilitate various potential applications for selective drug delivery. Viruses have significant implications in chemotherapy, gene transfer, vaccine production, immunotherapy and molecular imaging.