Improvements in HOMA indices and pancreatic endocrinal tissues in type 2-diabetic rats by DPP-4 inhibition and antioxidant potential of an ethanol fruit extract of Withania coagulans.

Heera RamPramod KumarAshok PurohitPriya KashyapSuresh KumarShivani KumarGarima SinghAbdulaziz A AlqarawiAbeer HashemElsayed Fathi Abd-AllahAl-Bandari Fahad Al-ArjaniBhim Pratap Singh

Published in: Nutrition & metabolism (2021)

It can be concluded that the phytoconstituents of an ethanol fruit extract of W. coagulans have the potential to inhibit DPP-4 which result in improved glucose homeostasis and restoration of pancreatic endocrinal tissues in type-2 diabetic rats.

Keyphrases

diabetic rats
oxidative stress
gene expression
anti inflammatory
human health
type diabetes
blood pressure
risk assessment