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Specific CD8+ TCR Repertoire Recognizing Conserved Antigens of SARS-CoV-2 in Unexposed Population: A Prerequisite for Broad-Spectrum CD8+ T Cell Immunity.

Wei HuMeifang HeXiaoning WangQiang SunMing Kuang
Published in: Vaccines (2021)
This study provides evidence of broad-spectrum SARS-CoV-2 specific CD8+ TCR repertoire in unexposed healthy population, which is implicated in the development and implementation of broad-spectrum vaccines against COVID-19.
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • regulatory t cells
  • healthcare
  • primary care
  • coronavirus disease
  • high throughput sequencing
  • nk cells
  • immune response