Current understanding of pineal gland structure and function in headache.
Mario Fernando Prieto PeresMarcelo M ValençaFernanda G AmaralJosé Cipolla-NetoPublished in: Cephalalgia : an international journal of headache (2019)
Melatonin has been used successfully as a treatment for migraine, cluster headaches and other headaches. There is a rationale for including the pineal gland as a relevant brain structure in the mechanisms of headache pathophysiology, and melatonin as a treatment option in primary headache.