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Single-cell DNA methylation sequencing by combinatorial indexing and enzymatic DNA methylation conversion.

Zac ChattertonPraves LamichhaneDiba Ahmadi RastegarLauren FitzpatrickHélène LebharChristopher MarquisGlenda HallidayJohn B Kwok
Published in: Cell & bioscience (2023)
To our knowledge sciEM represents the first non-bisulfite single-cell DNA methylation sequencing approach with single-base resolution.
Keyphrases
  • single cell
  • dna methylation
  • rna seq
  • genome wide
  • gene expression
  • high throughput
  • healthcare
  • copy number
  • hydrogen peroxide
  • nitric oxide