Post-transplant recurrence of steroid resistant nephrotic syndrome in children: the Italian experience.
William MorelloSairaj PuvinathanGiuseppe PuccioGian Marco GhiggeriLuca Dello StrologoLicia PeruzziLuisa MurerMichela CioniIsabella GuzzoEnrico CocchiElisa BenettiSara TestaLuciana GhioGianluca CaridiMassimo CardilloRosanna TorelliGiovanni MontiniPublished in: Journal of nephrology (2019)
Absence of a causative mutation represents the major risk factor for post-transplant recurrence in children with SRNS, while transplant can be curative in genetic SRNS. A prolonged time spent on dialysis before transplantation has no protective effect on the risk of relapse and should not be encouraged. Retransplantation represents a second chance after graft loss for recurrence.