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Post-transplant recurrence of steroid resistant nephrotic syndrome in children: the Italian experience.

William MorelloSairaj PuvinathanGiuseppe PuccioGian Marco GhiggeriLuca Dello StrologoLicia PeruzziLuisa MurerMichela CioniIsabella GuzzoEnrico CocchiElisa BenettiSara TestaLuciana GhioGianluca CaridiMassimo CardilloRosanna TorelliGiovanni Montini
Published in: Journal of nephrology (2019)
Absence of a causative mutation represents the major risk factor for post-transplant recurrence in children with SRNS, while transplant can be curative in genetic SRNS. A prolonged time spent on dialysis before transplantation has no protective effect on the risk of relapse and should not be encouraged. Retransplantation represents a second chance after graft loss for recurrence.
Keyphrases
  • free survival
  • young adults
  • chronic kidney disease
  • stem cells
  • gene expression
  • cell therapy
  • mesenchymal stem cells
  • peritoneal dialysis