Plasmodium falciparum histidine rich protein HRPII inhibits the anti-inflammatory function of antithrombin.

Peyman DinarvandLikui YangIndranil BiswasHemant GiriAlireza R Rezaie

Published in: Journal of thrombosis and haemostasis : JTH (2020)

We postulate that Pf-derived HRPII and polyphosphate can contribute to the pathogenesis of malaria infection by downregulating the AT-dependent anti-inflammatory and anticoagulant pathways.

Keyphrases

plasmodium falciparum
anti inflammatory
atrial fibrillation
venous thromboembolism
protein protein
amino acid
binding protein