Novel Intermittent Dosing Burst Paradigm in Spinal Cord Stimulation.

Timothy R DeerDenis G PattersonJavid BakshJason E PopePankaj MehtaAdil Raza Filippo Agnesi Krishnan V Chakravarthy

Published in: Neuromodulation : journal of the International Neuromodulation Society (2020)

ID burst SCS effectively relieved pain for six months. The largest group of subjects used IDB settings of 30 sec ON and 360 sec OFF. These findings present intriguing implications for the optimal "dose" of electricity in SCS and may offer many advantages such as optimizing the therapeutic window, extending battery life, reducing recharge burden and, potentially, mitigating therapy habituation or tolerance.

Keyphrases

spinal cord
neuropathic pain
high frequency
chronic pain
spinal cord injury
pain management
high intensity
risk factors
stem cells
mesenchymal stem cells