Small nucleolar RNA Sf-15 regulates proliferation and apoptosis of Spodoptera frugiperda Sf9 cells.
Bo WuLei HuangWujie QiuXiao LiuYawen ShenYiping LuZonglin YangXinmei LiBin CuiShidong XuHuili QiaoReng QiuLunguang YaoYunchao KanDandan LiPublished in: BMC molecular biology (2019)
We conclude that C/D box snoRNA Sf-15 can participate in apoptosis through regulating the expression of Ca2+-induced cell death pathway gene Cn in Sf9 cells. This is the first time that we found snoRNAs exhibiting dual functions in insect, which reveals a novel layer of ncRNA modulation in cell growth and death.
Keyphrases
- cell cycle arrest
- cell death
- induced apoptosis
- pi k akt
- endoplasmic reticulum stress
- oxidative stress
- signaling pathway
- squamous cell carcinoma
- binding protein
- high glucose
- transcription factor
- copy number
- diabetic rats
- genome wide
- gene expression
- endothelial cells
- drug induced
- nucleic acid
- genome wide identification
- zika virus