Login / Signup

Rational Control of Self-Recognition of Macroionic γ-Cyclodextrin by Host-Guest Interaction with Super-Chaotropic Borate Cluster Ions.

Jiahui ChenJiancheng LuoSelemon BekeleMesfin TsigeTianbo Liu
Published in: ChemPlusChem (2021)
We report a feasible method to control self-recognition during the self-assembly of a hydrophilic macroion, phosphate-functionalized γ-cyclodextrin (γ-CD-P), though host-guest interactions. We confirmed that γ-CD-P can form a host-guest complex with a super-chaotropic anion, namely the B12 F12 2- borate cluster, by using NMR spectroscopy and isothermal titration calorimetry. The loaded γ-CD-P, which has a higher charge density, can be distinguished from the uncomplexed γ-CD-P, leading to self-sorting behavior during the self-assembly process, confirmed by the formation of two types of individual supramolecular structures (Rh of ca. 57 nm and 18 nm, determined by light scattering) instead of hybrid structures in mixed dilute solution. This self-recognition behavior is accounted for by the difference in intermolecular electrostatic interactions arising from the loading.
Keyphrases
  • water soluble
  • nk cells
  • ionic liquid
  • photodynamic therapy
  • quantum dots
  • high resolution
  • drug delivery
  • mass spectrometry
  • molecular dynamics simulations
  • solid phase extraction
  • solar cells