Role of Necroptosis and Immune Infiltration in Human Stanford Type A Aortic Dissection: Novel Insights from Bioinformatics Analyses.
Fuqiang LiuTao WeiLin LiuFangxia HouCuixiang XuHua GuoWei ZhangMeijuan MaYulian ZhangQi YuJunkui WangPublished in: Oxidative medicine and cellular longevity (2022)
The present findings suggest that necroptosis phenomenon exists in TAAD and correlates with immune cell infiltration, which indicate necroptosis may promote the development of TAAD through activating immune infiltration and immune response. This study paves a new road to future investigation of the pathogenic mechanisms and therapeutic strategies for TAAD.