Cystic fibrosis with non-G551D gating mutations in Italy: Epidemiology and clinical characteristics.

Donatello SalvatoreVincenzo CarnovaleFabio MajoRita F PadoanMarco SalvatoreDomenica TaruscioAnnalisa AmatoGianluca FerrariGiuseppe Campagna

Published in: Pediatric pulmonology (2020)

Italian patients with GMs are few and are characterized by milder phenotypes than F/F patients. Improved outcomes are likely influenced by treatment with ivacaftor.

Keyphrases

cystic fibrosis
end stage renal disease
ejection fraction
newly diagnosed
pseudomonas aeruginosa
risk factors
combination therapy
air pollution
replacement therapy