Nivolumab and Ipilimumab as Maintenance Therapy in Extensive-Disease Small-Cell Lung Cancer: CheckMate 451.

Taofeek Kunle Owonikoko Keunchil Park Ramaswamy GovindanNeal ReadyMartin Reck Solange PetersShaker R DakhilAlejandro NavarroJerónimo Rafael Rodríguez-CidMichael SchenkerJong-Seok LeeVanesa GutierrezIvor PercentDaniel Morgensztern Carlos Henrique Barrios Laurent GreillierSofia BakaMiten PatelWen Hong LinGiovanni SelvaggiChristine BaudeletJonathan BadenDimple PandyaParul DoshiHye Ryun Kim

Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2021)

Maintenance therapy with nivolumab plus ipilimumab did not prolong OS for patients with ED-SCLC who did not progress on first-line chemotherapy. There were no new safety signals.

Keyphrases

small cell lung cancer
emergency department
stem cells
locally advanced
brain metastases
rectal cancer
mesenchymal stem cells
cell therapy
replacement therapy