Chronic exposure to lipopolysaccharides as an in vitro model to simulate the impaired odontogenic potential of dental pulp cells under pulpitis conditions.
Igor Paulino Mendes SoaresCaroline AnselmiMaria Luiza Barucci Araujo PiresRafael Antonio de Oliveira RibeiroMaria Luisa LeiteDiana Gabriela Soares Dos PassosCarlos Alberto de Souza CostaJosimeri HeblingPublished in: Journal of applied oral science : revista FOB (2023)
The exposure to 10 µg/mL LPS for seven days creates an inflammatory environment that is able to impair by more than half the odontogenic potential of HDPCs in vitro, simulating a pulpitis-like condition.