Amygdala enlargement in temporal lobe epilepsy: Histopathology and surgical outcomes.
Lubna ShakhatrehBenjamin SinclairCatriona McLeanElaine LuiAndrew P MorokoffJames A KingZhibin Chen MBiostatPiero PeruccaTerence J O'BrienPatrick KwanPublished in: Epilepsia (2024)
The presence of amygdala enlargement on the pre-operative brain MRI in patients with TLE does not affect the surgical outcome following ATL-AH, and it does not necessarily suggest abnormal histopathology. These findings suggest that amygdala enlargement might reflect a secondary reactive process to seizures in the epileptogenic temporal lobe.