Skin pigmentation polymorphisms associated with increased risk of melanoma in a case-control sample from southern Brazil.

Larissa B ReisRenato M BakosFernanda Sales Luiz ViannaGabriel S MacedoVanessa C JacovasAndré M Ribeiro-Dos-SantosSidney SantosLúcio BakosPatricia Ashton-Prolla

Published in: BMC cancer (2020)

These results contribute to the current knowledge and indicate that epistatic interaction of these SNPs, with an additive or correlational effect, may be involved in modulating the risk of melanoma in individuals from a geographic region with a high incidence of the disease.

Keyphrases

case control
skin cancer
healthcare
risk factors
genome wide
signaling pathway
basal cell carcinoma
soft tissue
gene expression