Assessing safety concerns of interstitial lung disease associated with antibody-drug conjugates: a real-world pharmacovigilance evaluation of the FDA adverse event reporting system.
Wanlong LinJiabing XuYufang LiaoXiuxian LinJianhui YangWei ZhuangPublished in: International journal of clinical pharmacy (2023)
This real-world study highlights high safety signals of interstitial lung disease associated with antibody-drug conjugates. Clinicians should be aware of these safety concerns and risk factors and implement early identification measures for their patients. Future research should prioritize comprehensively exploring the relationship between antibody-drug conjugates and lung diseases.
Keyphrases
- interstitial lung disease
- systemic sclerosis
- rheumatoid arthritis
- idiopathic pulmonary fibrosis
- risk factors
- adverse drug
- end stage renal disease
- ejection fraction
- cancer therapy
- chronic kidney disease
- newly diagnosed
- palliative care
- prognostic factors
- drug delivery
- patient reported outcomes
- current status
- electronic health record
- drug induced