Next-generation sequencing of HLA: validation and identification of new polymorphisms in a Brazilian population.

Raquel Aparecida Fabreti-OliveiraCintia K F OliveiraEliane M G ValeEvaldo Nascimento

Published in: HLA (2020)

We have successfully validated NGS HLA typing despite numerous challenges, contributing to the identification of novel alleles that impact on HLA matching and antibody evaluation in organ and tissue transplantation.

Keyphrases

bioinformatics analysis
gene expression
bone marrow
circulating tumor
circulating tumor cells