Magnetic metal phenolic networks: expanding the application of a promising nanoprobe to phosphoproteomics research.

Huimin ChuHaoyang ZhengJizong Yao Nianrong SunGuoquan YanChun-Hui Deng

Published in: Chemical communications (Cambridge, England) (2021)

A Ti-tannic acid modified magnetic nanoprobe was synthesized via one step, and applied to phosphopeptide extraction. 3456 phosphopeptides and 1285 phosphoproteins were finally identified from 100 μg HeLa cell extracts. This opens up a new avenue for metal phenolic networks in phosphoproteomics research.

Keyphrases

molecularly imprinted
living cells
single cell
cell therapy
fluorescent probe
high resolution
cell proliferation
mesenchymal stem cells
solid phase extraction
oxide nanoparticles
liquid chromatography