Impact of valve morphology, hypertension and age on aortic wall properties in patients with coarctation: a two-centre cross-sectional study.
Niky GhorbaniVivek MuthuranguAbbas KhushnoodLeonid GoubergritsSarah NordmeyerJoao Filipe FernandesChong-Bin LeeKilian RunteSophie RothStephan SchubertSebastian KelleFelix BergerTitus KuehneMarcus KelmPublished in: BMJ open (2020)
From early adolescence on, both arterial hypertension and BAVD have a major impact on aortic distensibility. Their specific effects differ in strength and localisation (descending vs ascending aorta). Moreover, adequate blood pressure control is associated with improved distensibility. These findings could contribute to the understanding of cardiovascular complications and the management of patients with aortic coarctation.
Keyphrases
- aortic valve
- arterial hypertension
- pulmonary artery
- blood pressure
- aortic dissection
- transcatheter aortic valve replacement
- aortic stenosis
- left ventricular
- coronary artery
- pulmonary hypertension
- pulmonary arterial hypertension
- depressive symptoms
- risk factors
- mitral valve
- heart failure
- weight loss
- atrial fibrillation