The incidence, clinical outcome, and protective factors of mixed chimerism following hematopoietic stem cell transplantation for severe aplastic anemia.
Zheng-Li XuYi-Fei ChengYuan-Yuan ZhangXiao-Dong MoTing-Ting HanFeng-Rong WangChen-Hua YanYu-Qian SunYu-Hong ChenFei-Fei TangWei HanYu WangXiao-Hui ZhangKai-Yan LiuXiao-Jun HuangLan-Ping XuPublished in: Clinical transplantation (2021)
Mixed chimerism was an unsettling status even in non-malignancy. Haploidentical transplantation with more intense regimen by adding Bu to Cy and ATG was associated with reduced MC following HSCT for SAA. An intensified regimen should be explored in matched related or unrelated donors.
Keyphrases
- allogeneic hematopoietic stem cell transplantation
- acute myeloid leukemia
- acute lymphoblastic leukemia
- cord blood
- stem cell transplantation
- chronic kidney disease
- bone marrow
- risk factors
- peripheral blood
- early onset
- iron deficiency
- kidney transplantation
- cell therapy
- hematopoietic stem cell
- low dose
- mesenchymal stem cells
- high dose