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Brain malformations and cognitive performance in spina bifida.

Joanna SchneiderNaomi MohrNiko AliatakisUlrich SeidelRainer JohnGabriel PromnitzBirgit SporsAngela M Kaindl
Published in: Developmental medicine and child neurology (2020)
Brain malformations occur more frequently in spina bifida aperta (SBA) than in spina bifida occulta (SBO). Cognitive impairment is less frequent in SBO. Hydrocephalus, stenogyria, midbrain, and corpus callosum abnormalities are associated with lower cognitive function. Difference in prognosis in SBO versus SBA can alter prenatal counselling.
Keyphrases
  • cognitive impairment
  • resting state
  • white matter
  • functional connectivity
  • pregnant women
  • cerebral ischemia
  • subarachnoid hemorrhage
  • multiple sclerosis
  • cerebrospinal fluid
  • blood brain barrier