Role of inflammation in pediatric irritable bowel syndrome.

Giovanni Di Nardo Cesare Cremon Annamaria Staiano Vincenzo Stanghellini Osvaldo BorrelliCaterina StrisciuglioClaudio RomanoSaverio MallardoElena ScarpatoGiovanni MarascoSilvia SalvatoreLetizia ZenzeriEnrico FeliciLicia PensabeneSimona SestitoRuggiero FrancavillaPaolo QuitadamoMariella BaldassarreValentina Giorgio Renato TambucciChiara ZiparoPasquale ParisiMaria Raffaella BarbaroGiovanni Barbaranull null

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2022)

The aim of this review is to summarize the main evidence on the presence of low-grade inflammation and immune activation in children with IBS, its possible role in symptom generation, and its potential implication for new therapeutic strategies.

Keyphrases

irritable bowel syndrome
low grade
oxidative stress
high grade
young adults
patient reported