Intensive induction regimens after deferring initial therapy for mantle cell lymphoma are not associated with improved survival.
Krithika ShanmugasundaramSubir GoyalJeffery SwitchenkoOscar CalzadaMichael C ChurnetskiBhaskar KollaVeronika BachanovaJames N GersonStefan K BartaMax J GordonAlexey V DanilovNatalie S GroverStephanie MathewsMadelyn BurkartReem KarmaliYazeed SawalhaBrian T HillNilanjan GhoshSteven I ParkNarendranath EpperlaDavid A BondTalha BadarKristie A BlumMehdi HamadaniTimothy S FenskeMary MalecekBrad S KahlPeter MartinJin GuoChristopher R FlowersJonathon B CohenPublished in: European journal of haematology (2021)
These results indicate that intensified initial treatment is not associated with improved survival after deferring initial therapy, although prospective studies are needed to determine which of these patients with MCL may benefit from intensive therapy.