The effect of probiotic administration on metabolomics and glucose metabolism in CF patients.

Michal GurNehama Zuckerman-LevinKamal MasarwehMoneera HannaLuca LaghiMassimiliano MarazzatoShir LevanonFahed HakimRonen Bar-YosephMichael WilschanskiLea Bentur

Published in: Pediatric pulmonology (2022)

Changes in urine and stool metabolic profiles, following the administration of probiotics, may suggest a positive effect on glucose metabolism in CF. Larger long-term studies are needed to confirm our findings. Understanding the interplay between dysbiosis, inflammation, and glucose metabolism may help preventing CFRD.

Keyphrases

cystic fibrosis
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
mass spectrometry
oxidative stress
prognostic factors