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Diagnosis and Treatment of Sleep Apnea in Children: A Future Perspective Is Needed.

Esther Solano-PérezCarlota CosoMaría Castillo-GarcíaSofía Romero-PeraltaSonia Lopez-MonzoniEduardo LaviñaIrene Cano-PumaregaManuel Sánchez-de-la-TorreFrancisco García-RíoOlga Mediano
Published in: Biomedicines (2023)
Obstructive sleep apnea (OSA) in children is a prevalent, but still, today, underdiagnosed illness, which consists of repetitive episodes of upper airway obstruction during sleep with important repercussions for sleep quality. OSA has relevant consequences in the pediatric population, mainly in the metabolic, cardiovascular (CV), and neurological spheres. However, contrary to adults, advances in diagnostic and therapeutic management have been scarce in the last few years despite the increasing scientific evidence of the deleterious consequences of pediatric OSA. The problem of underdiagnosis and the lack of response to treatment in some groups make an update to the management of OSA in children necessary. Probably, the heterogeneity of OSA is not well represented by the classical clinical presentation and severity parameters (apnea/hypopnea index (AHI)), and new strategies are required. A specific and consensus definition should be established. Additionally, the role of simplified methods in the diagnosis algorithm should be considered. Finally, the search for new biomarkers for risk stratification is needed in this population. In conclusion, new paradigms based on personalized medicine should be implemented in this population.
Keyphrases
  • obstructive sleep apnea
  • positive airway pressure
  • sleep apnea
  • sleep quality
  • young adults
  • machine learning
  • physical activity
  • high frequency
  • brain injury
  • blood brain barrier