Clinical and neuroimaging risk factors associated with the development of intracerebral hemorrhage while taking direct oral anticoagulants.
Alvin S DasElif GökçalRobert William RegenhardtAndrew D WarrenAlessandro BiffiJoshua N GoldsteinW Taylor KimberlyAnand ViswanathanLee H SchwammJonathan RosandSteven M GreenbergM Edip GurolPublished in: Journal of neurology (2022)
Risk factors including diabetes, prior stroke, and smoking history as well as MRI biomarkers including CMBs and cSS are associated with ICH in DOAC users. Although screening MRIs are not typically performed prior to initiating DOAC therapy, these data suggest that patients of high-hemorrhagic risk may be identified.
Keyphrases
- direct oral anticoagulants
- atrial fibrillation
- venous thromboembolism
- risk factors
- end stage renal disease
- type diabetes
- ejection fraction
- cardiovascular disease
- chronic kidney disease
- newly diagnosed
- magnetic resonance imaging
- brain injury
- stem cells
- peritoneal dialysis
- patient reported outcomes
- electronic health record
- metabolic syndrome
- blood brain barrier
- mesenchymal stem cells
- adipose tissue
- bone marrow
- cell therapy
- artificial intelligence