Geographic differences in the incidence of Huntington's disease in Sardinia, Italy.
Antonella MuroniMaria R MurruLucia UlgheriMargherita SechiTommaso ErcoliFrancesco MarrosuCesa L ScaglioneAnna Rita BentivoglioMartina PetraccaPaola SoliveriEleonora CoccoStefania CuccuMarcello DeriuChiara ZuccatoGiovanni DefazioPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2021)
The overall incidence of HD in Sardinia is close to the correspondent estimates in Mediterranean countries. Our findings highlight also the possibility of local microgeographic variations in the epidemiology of HD that might reflect several factors, including a possible founder effect in the rural areas of South Sardinia and Nuoro.
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