Evodiamine Inhibits Gastric Cancer Cell Proliferation via PTEN-Mediated EGF/PI3K Signaling Pathway.

Ruichuang YangJian-Xia Wen Tao YangChunmei DaiYan-Ling Zhao

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

Evodiamine inhibited the directional migration and invasion of GC cells by inhibiting PTEN-mediated EGF/PI3K signaling pathway. These findings revealed that evodiamine might serve as a potential candidate for the treatment or prevention of GC.

Keyphrases

pi k akt
signaling pathway
cell cycle arrest
induced apoptosis
cell proliferation
epithelial mesenchymal transition
growth factor
gas chromatography
cell cycle
oxidative stress
cell death
high resolution
tandem mass spectrometry
smoking cessation
simultaneous determination
replacement therapy