Base-Promoted Reaction of 4-Chloro-3-vinyl Coumarins, Phenacylpyridinium Bromides, and Elemental Sulfur: A Designed Approach to Thiopyrano[4,3- c ]chromen-5(1 H )-ones.
Behnaz FarajpourAbdolali AlizadehPublished in: The Journal of organic chemistry (2022)
A designed synthesis of thiopyrano[4,3- c ]chromen-5(1 H )-ones was developed based on a base-promoted three-component reaction between 4-chloro-3-vinyl coumarins, phenacylpyridinium bromides, and elemental sulfur. Readily available starting materials, mild conditions, chemoselectivity, operational simplicity, and synthetically useful yields are some highlighted advantages of these transformations.
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