Dementia in Rare Genetic Neurodevelopmental Disorders: A Systematic Literature Review.

Hadassa KwetsieMalu van Schaijk Sven J Van der LeeDederieke Maes-FestenLeontine W Ten HoopenMieke M van HaelstMichael CoesmansEsther Van Den BergMarie Claire Y De WitYolande PijnenburgEleonora M A Aronica Erik BootAgnies M Van Eeghen

Published in: Neurology (2024)

Currently available literature shows limited information on aging in RGNDs, with relatively many reports of young-onset dementia. Longitudinal data may provide insights into converging neurodevelopmental degenerative pathways. We provide recommendations to optimize dementia screening, diagnosis, and research.

Keyphrases

mild cognitive impairment
cognitive impairment
systematic review
genome wide
emergency department
gene expression
congenital heart disease
copy number
middle aged
adverse drug
social media