DNA repair in lung cancer: a large-scale quantitative analysis for polymorphisms in DNA repairing pathway genes and lung cancer susceptibility.

Zexi LiaoMinhan YiJiaxin LiYuan Zhang

Published in: Expert review of respiratory medicine (2022)

There are five SNPs in DNA repairing pathway associated with increased LC risk and four others decreased LC risk. Besides, the risky SNPs in different ethnicities and various LC subtypes were partly different, and the contribution of different genotypes to risk alleles were various as well.

Keyphrases

dna repair
genome wide
dna damage
simultaneous determination
circulating tumor
single molecule
mass spectrometry
gene expression
oxidative stress
transcription factor