2.5-Year changes of connectivity dynamism are relevant for physical and cognitive deterioration in multiple sclerosis.

Maria Assunta RoccaGiulia D'AmorePaola ValsasinaNicolò TedoneAlessandro Meani Massimo Filippi

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2024)

At 2.5-year follow-up, default-mode network TVFC reductions were found in worsening MS. Moreover, reduced deep gray matter TVFC characterized physically worsened patients, whereas precuneus involvement characterized cognitively worsened MS patients.

Keyphrases

multiple sclerosis
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
mass spectrometry
prognostic factors
peritoneal dialysis
ms ms
physical activity
functional connectivity
mental health
resting state
cognitive decline
mild cognitive impairment