Associations between diabetes-related genetic risk scores and residual beta cell function in type 1 diabetes: the GUTDM1 study.

Coco M Fuhri Snethlage Manon Balvers Bart Ferwerda Elena Rampanelli Pleun de Groen Bart O Roep Hilde J Herrema Timothy James McDonald Daniel H van Raalte Michael N Weedon Richard D Oram Max Nieuwdorp Nordin M J Hanssen

Published in: Diabetologia (2024)

Diabetes-related GRS are associated with residual beta cell function in individuals with type 1 diabetes. These findings suggest some genetic contribution to preservation of beta cell function.

Keyphrases

type diabetes
glycemic control
cardiovascular disease
genome wide
insulin resistance
copy number
adipose tissue
metabolic syndrome
skeletal muscle