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The Structure of the Drp1 Lattice on Membrane.

Ruizhi PengKristy RochonScott M StaggJason A Mears
Published in: bioRxiv : the preprint server for biology (2024)
This study provides new insights into the structure of Drp1 on lipid membranes. A locally ordered Drp1 lattice structure is solved and reveals intermolecular contacts and conformational rearrangements that suggest a mechanism for constriction of mitochondrial membranes.
Keyphrases
  • oxidative stress
  • molecular dynamics
  • molecular dynamics simulations