ERG Regulates Lymphatic Vessel Specification Genes and Its Deficiency Impairs Wound Healing-Associated Lymphangiogenesis.

Takashi YamashitaUlas KaplanAdri ChakrabortyGrace MardenSami GritliDaniel RohAndreea BujorMarcin TrojanowskiGiovanni LigrestiJeffrey L BrowningMaria Trojanowska

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2024)

ERG and FLI-1 are essential regulators of blood and lymphatic vessel regeneration. Deficiency of ERG and FLI-1 in SSc endothelial cells may contribute to the impairment of blood and lymphatic vasculature in patients with SSc.

Keyphrases

lymph node
wound healing
endothelial cells
stem cells
genome wide
dna methylation
high glucose
vascular endothelial growth factor
cell fate