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Cryptotanshinone from Salvia miltiorrhiza Bunge (Danshen) inhibited inflammatory responses via TLR4/MyD88 signaling pathway.

Xin-Xing LiXiaoting ZhengZhenjie LiuQiongming XuHongzhen TangJianfang FengShilin YangChi Teng VongHongwei GaoYitao Wang
Published in: Chinese medicine (2020)
Collectively, we suggested that CPT exerted significant anti-inflammatory effects via modulating TLR4-MyD88/PI3K/Nrf2 and TLR4-MyD88/NF-κB/MAPK pathways.
Keyphrases
  • toll like receptor
  • signaling pathway
  • nuclear factor
  • pi k akt
  • inflammatory response
  • immune response
  • oxidative stress
  • induced apoptosis
  • epithelial mesenchymal transition
  • lps induced
  • endoplasmic reticulum stress