Temporal changes in clinical and radiographic variables in dogs with preclinical myxomatous mitral valve disease: The EPIC study.
Adrian BoswoodSonya G GordonJens HäggströmMartin VanselowGerhard WessRebecca L StepienMark A OyamaBruce W KeeneJohn BonaguraKristin A MacDonaldMark PattesonSarah SmithPhillip R FoxKaren SandersonRichard WoolleyViktor SzatmáriPierre MenautWhitney M ChurchM Lynne O'SullivanJean-Philippe JaudonJan-Gerd KreskenJohn E RushKirstie A BarrettSteven L RosenthalAshley B SaundersIngrid LjungvallMichael DeinertEric BomassiAmara H EstradaMaria J Fernandez Del PalacioN Sydney MoiseJonathan A AbbottYoko FujiiAlan SpierMichael W LuethyRoberto A SantilliMasami UechiAnna TidholmChristoph SchummerPhilip WatsonPublished in: Journal of veterinary internal medicine (2020)
Dogs with MMVD and cardiomegaly experience increases in HR, RR, RRR, and VHS, and decreases in BW and RT as they develop CHF. The variables with highest absolute change and rate of change were RR and RRR. These findings reinforce the value of RR and RRR as indicators of impending or incipient CHF.