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Determinants of selection in yeast evolved by genome shuffling.

Damien Biot-PelletierDominic PinelKane LarueVincent J J Martin
Published in: Biotechnology for biofuels (2018)
We use these data to propose a model of inhibitor tolerance in our GS mutants. Our results also suggest a role for compensatory evolution and epistasis in our genome shuffling experiment and illustrate the impact of historical contingency on the outcomes of evolutionary engineering.
Keyphrases
  • genome wide
  • electronic health record
  • dna methylation
  • big data
  • metabolic syndrome
  • machine learning
  • cell wall
  • skeletal muscle
  • artificial intelligence