Association of Long-Term Blood Pressure Variability with Cerebral Amyloid Angiopathy-related Brain Injury and Cognitive Decline.
Lukas SveikataMaria Clara Zanon ZotinDorothee SchoemakerYuan MaValentina PerosaAnthipa ChokesuwattanaskulCharidimou AndreasMarco DueringEdip M GurolFrédéric AssalSteven M GreenbergAnand ViswanathanPublished in: medRxiv : the preprint server for health sciences (2024)
Long-term BPV has a dose-dependent association with alterations in white matter integrity, lobar lacunes, and cortical cerebral microinfarcts, and predicts cognitive decline. Controlling BPV is a potential strategic approach to prevent cognitive decline, especially in early-stage CAA.