Statin-boosted cellular uptake and endosomal escape of penetratin due to reduced membrane dipole potential.
Gyula BattaLevente KárpátiGabriela Fulaneto HenriqueGabriella TóthSzabolcs TarapcsákTamas KovacsFlorina ZakanyIstván M MándityPeter NagyPublished in: British journal of pharmacology (2021)
These results highlight the importance of the dipole potential in regulating cellular uptake of cell penetrating peptides and suggest a clinically relevant way of boosting this process.