Perindopril in Breast Milk and Determination of Breastfed Infant Exposure: A Prospective Observational Study.

Catherine LeggettEi Mon Phyo LwinUsha RitchieYunmei SongJacobus P GerberSean TurnerWilliam Bill HagueMichael StarkRichard N Upton Sanjay Garg

Published in: Drug design, development and therapy (2020)

Infant exposure to perindopril and perindoprilat through breast milk is low. However, some infants were found to have plasma perindoprilat concentrations consistent with pharmacodynamic effects. Perindopril may be used in mothers of healthy term infants, provided the infant is carefully monitored.

Keyphrases

hypertensive patients
arterial hypertension
preterm infants
high resolution
gestational age
preterm birth