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Expitope 2.0: a tool to assess immunotherapeutic antigens for their potential cross-reactivity against naturally expressed proteins in human tissues.

Victor JaravineAnja MöschSilke RaffegerstDolores J SchendelDmitrij Frishman
Published in: BMC cancer (2017)
The ability to predict potential side effects in normal tissues helps in the development and selection of safer antigens, enabling more successful immunotherapy of cancer and other diseases.
Keyphrases
  • gene expression
  • endothelial cells
  • dendritic cells
  • human health
  • squamous cell
  • induced pluripotent stem cells
  • squamous cell carcinoma
  • immune response
  • risk assessment
  • lymph node metastasis